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ID: ALA3271950

Journal: J Med Chem

Title: 2,3-Dihydroxyphenethanolamine as an adrenergic agent.

Authors: Bartholow RB, Walaszek EJ.

Abstract: In an attempt to further define the role of the m-hydroxy group in adrenergic agents, 2,3-dihydroxyphenethanolamine hydrobromide and N-isopropyl-2,3-dihydroxyphenethanolamine hydrobromide were prepared. These agents are less active than norepinephrine in alpha- and beta-adrenergic in vitro tests. The synthesis and conclusions from the tests are discussed.

CiteXplore: 1246044

DOI: 10.1021/jm00223a039