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ID: ALA3272154

Journal: J Med Chem

Title: Synthesis of 1- and 2-substituted indazoles as anthelmintic agents.

Authors: Kingsbury WD, Gyurik RJ, Theodorides VJ, Parish RC, Gallagher G.

Abstract: Selective synthesis of 1- and 2-acyl-, alkoxycarbonyl-, and carbamoylindazoles are described. Spectroscopic data which were the basis for structural assignments are presented. These compounds, particularly methyl 2H-indazole-2-carboxylate and N-heptyl-N-methyl-2H-indazole-2-carboxamide, lack the spectrum of anthelmintic activity of the benzimidazole and benzotriazole anthelmintics to which they are structurally related.

CiteXplore: 950654

DOI: 10.1021/jm00228a021