Basic Information
ID: ALA3272304
Journal: J Med Chem
Title: Syntheses of heterocylic fused thiazole acetic acids. 2.
Authors: Bell SC, Wei PH.
Abstract: A number of tricyclic and bicyclic fused thiazole-2-acetic acid derivatives were prepared and the chemistry and biological properties of these compounds are discussed. Many of the esters exhibited antitubercular activity. The bicyclic thiazole-2-acetic acids had antidepressant activity. Interesting antimetastatic activity against Lewis lung tumor in mice was found with several compounds, in particular, the thiazolo[3,2-a]benzimidazole-2-acetic acid derivative XI.
CiteXplore: 1263204
DOI: 10.1021/jm00226a016
Patent ID: ┄
Associated Items: Associated Bioactivities Associated Assays Associated Compounds Associated Targets