Chemical constituents from Eucalyptus citriodora Hook leaves and their glucose transporter 4 translocation activities.

Basic Information

ID: ALA3297643

Journal: Bioorg Med Chem Lett

Title: Chemical constituents from Eucalyptus citriodora Hook leaves and their glucose transporter 4 translocation activities.

Authors: Wang C, Yang J, Zhao P, Zhou Q, Mei Z, Yang G, Yang X, Feng Y.

Abstract: Bioassay-guided phytochemical investigation of the EtOAc fraction from the leaves of a Chinese medicinal herb, Eucalyptus citriodora Hook, resulted in the isolation of a new compound rhodomyrtosone E (1), along with 12 known compounds (2-13). The structure of the new compound was established by 1D and 2D NMR, MS data and X-ray crystallographic analysis. Betulinic acid (2) and corosolic acid (5) increased glucose transporter 4 (GLUT-4) translocation by 2.38 and 1.78-fold, respectively.

CiteXplore: 24894556

DOI: 10.1016/j.bmcl.2014.05.014

Patent ID: