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ID: ALA3351622

Journal: Eur J Med Chem

Title: Synthesis and evaluation of 9-deoxy analogues of (-)-thysanone, an inhibitor of HRV 3C protease.

Authors: Young Jeong J, Sperry J, Taylor JA, Brimble MA.

Abstract: 9-Deoxy analogues of the HRV 3C protease inhibitor (-)-thysanone display better inhibitory properties than the natural product, inferring the C9-OH hinders binding to the enzyme.

CiteXplore: 25259514

DOI: 10.1016/j.ejmech.2014.09.063