Document Report Card

ID: ALA3351772

Journal: J Nat Prod

Title: Xenortide Biosynthesis by Entomopathogenic Xenorhabdus nematophila.

Authors: Reimer D, Nollmann FI, Schultz K, Kaiser M, Bode HB.

Abstract: The biosynthesis gene cluster of the xenortides and a new derivative, xenortide D, which is produced in only trace amounts, was identified in Xenorhabdus nematophila. The structure of xenortide D was elucidated using a combination of labeling experiments followed by MS analysis and was confirmed by synthesis. Bioactivity tests revealed a weak activity of tryptamine-carrying xenortides against Plasmodium falciparum and Trypanosoma brucei.

CiteXplore: 25080196

DOI: 10.1021/np500390b