Pyrrole alkaloids from the fruits of Morus alba.

Basic Information

ID: ALA3351927

Journal: Bioorg Med Chem Lett

Title: Pyrrole alkaloids from the fruits of Morus alba.

Authors: Kim SB, Chang BY, Hwang BY, Kim SY, Lee MK.

Abstract: Phytochemical investigation of the fruits of Morus alba afforded seventeen pyrrole alkaloids including five new compounds. The structures of five new pyrrole alkaloids, named morroles B-F (4, 5, 7, 16 and 17), were determined on the basis of spectroscopic interpretations. 4-[Formyl-5-(hydroxymethyl)-1H-pyrrol-1-yl]butanoate (2) was synthesized by chemical reaction but first isolated from nature. Among isolated compounds, compounds 6 and 14 significantly inhibited pancreatic lipase activity.

CiteXplore: 25467154

DOI: 10.1016/j.bmcl.2014.10.073

Patent ID: