Novel azoles as potent and selective cannabinoid CB2 receptor agonists.

ID: ALA3580586

Journal: Bioorg Med Chem Lett

Title: Novel azoles as potent and selective cannabinoid CB2 receptor agonists.

Authors: Harnett JJ, Dolo C, Viossat I, Auger F, Ferrandis E, Bigg D, Auguet M, Auvin S, Chabrier PE.

Abstract: Novel azole compounds were prepared which demonstrated potent hCB2 binding activities with antioxidant activity for a selected compound. These compounds show good selectivity over the hCB1 receptor and are full agonists at the hCB2 receptor.

CiteXplore: 25466197

DOI: 10.1016/j.bmcl.2014.11.003

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