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ID: ALA3804760
Journal: Bioorg Med Chem Lett
Title: Serralongamines B-D, three new Lycopodium alkaloids from Lycopodium serratum var. longipetiolatum, and their inhibitory effects on foam cell formation in macrophages.
Authors: Ishiuchi K, Jiang WP, Fujiwara Y, Wu JB, Kitanaka S.
Abstract: Three new Lycopodium alkaloids, serralongamines B-D (1-3), have been isolated from the club moss Lycopodium serratum var. longipetiolatum, and the structures were elucidated on the basis of spectroscopic data and chemical transformation. 1 and 3 significantly exhibited the inhibitory activity against foam cell formation in human macrophages, one of characteristic features of early atherosclerotic lesions.
CiteXplore: 27086123