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ID: ALA3808350
Journal: ACS Med Chem Lett
Title: Stacking with No Planarity?
Authors: Gunaydin H, Bartberger MD.
Abstract: This viewpoint describes the results obtained from matched molecular pair analyses and quantum mechanics calculations that show unsaturated rings found in drug-like molecules may be replaced with their saturated counterparts without losing potency even if they are engaged in stacking interactions with the side chains of aromatic residues.
CiteXplore: 27096037