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ID: ALA3822393

Journal: J Med Chem

Title: An Advanced Tool To Interrogate BRD9.

Authors: Karim RM, Schönbrunn E.

Abstract: Selective inhibitors of bromodomain-containing protein 9 (BRD9) may have therapeutic potential in the treatment of human malignancies and inflammatory diseases. A selective small molecule inhibitor that is well tolerated and has proper pharmacokinetic properties is required to explore the function of BRD9 in diseases. BI-9564 (2) is a cell permeable and noncytotoxic BRD9 inhibitor provided to the scientific community to explore BRD9 biology and determine its potential as a drug target.

CiteXplore: 27120693

DOI: 10.1021/acs.jmedchem.6b00550