Document Report Card

Basic Information

ID: ALA3856245

Journal: Bioorg Med Chem Lett

Title: New labdane diterpenoids from Croton laui and their anti-inflammatory activities.

Authors: Yang L, Zhang YB, Chen LF, Chen NH, Wu ZN, Jiang SQ, Jiang L, Li GQ, Li YL, Wang GC.

Abstract: Nine new labdane diterpenoids (1-9) were isolated from the aerial parts of Croton laui, along with eight known analogues (10-17). Their structures were identified on the basis of the spectral data (IR, UV, HRESIMS, 1D and 2D NMR), and the structure of 8 was confirmed by single crystal X-ray diffraction analyses. In addition, compounds 1, 4, 7, 8, and 14 showed weak anti-inflammatory activities in LPS-stimulated RAW 264.7 cells.

CiteXplore: 27575472

DOI: 10.1016/j.bmcl.2016.08.052