Radical scavenging and antibacterial activity of caffemides against gram positive, gram negative and clinical drug resistance bacteria.

Basic Information

ID: ALA3868627

Journal: Bioorg Med Chem Lett

Title: Radical scavenging and antibacterial activity of caffemides against gram positive, gram negative and clinical drug resistance bacteria.

Authors: Misra K, Maity HS, Nag A, Sonawane A.

Abstract: A new series of caffemide were synthesized and their antioxidant and antibacterial activities were explored. Antioxidant and antibacterial activities were measured of different structures of caffemide containing different functional groups. Anti-oxidative caffemides 1b and 1g showed significantly higher activity against different bacteria with MIC values less than 50μg/ml. These anti-oxidative and antibacterial properties of caffemides might be helpful for the treatment of secondary infections and discovery of new antibiotics.

CiteXplore: 27865704

DOI: 10.1016/j.bmcl.2016.10.089

Patent ID: