Document Report Card
Basic Information
ID: ALA4004792
Journal: J Nat Prod
Title: Monascustin, an Unusual γ-Lactam from Red Yeast Rice.
Authors: Wei W, Lin S, Chen M, Liu T, Wang A, Li J, Guo Q, Shang X.
Abstract: Monascustin (1), an unusual γ-lactam, was isolated from an ethanol extract of the Monascus purpureus fermented rice. Its structure including the absolute configuration was determined by spectroscopic data analysis and confirmed by X-ray crystallography. A plausible biosynthetic pathway is discussed on the basis of amino acid derivatization. Compound 1 showed inhibitory activity against histone deacetylase 1.
CiteXplore: 28026946