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ID: ALA4041472
Journal: J Nat Prod
Title: Curacin E from the Brittle Star Ophiocoma scolopendrina.
Authors: Ueoka R, Hitora Y, Ito A, Yoshida M, Okada S, Takada K, Matsunaga S.
Abstract: Bioassay-guided fractionation of the extract of the brittle star Ophiocoma scolopendrina afforded curacin E (1), a congener of curacin A (2). Curacin A (2) is an antimitotic agent of cyanobacterial origin. The structure of curacin E was studied by interpretation of NMR data and the ECD spectrum. Curacin E has an ethylcarbonyl terminus in its side chain and inhibits the proliferation of P388 cells.
CiteXplore: 27684202