Lactone Derivatives Produced by a Phaeoacremonium sp., an Endophytic Fungus from Senna spectabilis.

Basic Information

ID: ALA4118037

Journal: J Nat Prod

Title: Lactone Derivatives Produced by a Phaeoacremonium sp., an Endophytic Fungus from Senna spectabilis.

Authors: Silva GH, Zeraik ML, de Oliveira CM, Teles HL, Trevisan HC, Pfenning LH, Nicolli CP, Young MCM, Mascarenhas YP, Abreu LM, Saraiva AC, Medeiros AI, Bolzani VDS, Araujo AR.

Abstract: Three new isoaigialones, A, B, and C (1-3), along with aigialone (4), were isolated from the crude EtOAc extract of a Phaeoacremonium sp., an endophytic fungus obtained from the leaves of Senna spectabilis. The structures of these compounds were elucidated based on the analysis of spectroscopic data. Compounds 2 and 4 were active against the phytopathogenic fungi Cladosporium cladosporioides and C. sphaerospermum. This is the first report of metabolites produced by an Phaeoacremonium sp., associated with S. spectabilis.

CiteXplore: 28425292

DOI: 10.1021/acs.jnatprod.5b00828

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