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ID: ALA4138294

Journal: J Nat Prod

Title: Cybastacines A and B: Antibiotic Sesterterpenes from a Nostoc sp. Cyanobacterium.

Authors: Cabanillas AH, Tena Pérez V, Maderuelo Corral S, Rosero Valencia DF, Martel Quintana A, Ortega Doménech M, Rumbero Sánchez Á.

Abstract: Cybastacines A (1) and B (2) were discovered as a novel pentacyclic sesterterpenoid-alkaloid skeleton structure, with a guanidinium group. These molecules were isolated from a Nostoc sp. cyanobacterium collected in the Canary Islands. Their structures were elucidated primarily by a combination of spectroscopic analyses and X-ray diffraction. These compounds showed antibiotic activities against several clinically relevant bacterial strains.

CiteXplore: 29432010

DOI: 10.1021/acs.jnatprod.7b00638