Expanding the tetrahydroquinoline pharmacophore.

ID: ALA4184140

Journal: Bioorg Med Chem Lett

Title: Expanding the tetrahydroquinoline pharmacophore.

Authors: Goli N, Mainkar PS, Kotapalli SS, K T, Ummanni R, Chandrasekhar S.

Abstract: Tetrahydroquinoline is a privileged scaffold with a large number of biological applications. The tetrahydroquinoline pharmacophore has been expanded to yield 34 compounds. Biological screening of these compounds led to the identification of tetrahydroquinoline as neurotropic agents not reported earlier.

CiteXplore: 28318941

DOI: 10.1016/j.bmcl.2017.02.077

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