Taichunins A-D, Norditerpenes from Aspergillus taichungensis (IBT 19404).

Basic Information

ID: ALA4316640

Journal: J Nat Prod

Title: Taichunins A-D, Norditerpenes from Aspergillus taichungensis (IBT 19404).

Authors: Kato H, Sebe M, Nagaki M, Eguchi K, Kagiyama I, Hitora Y, Frisvad JC, Williams RM, Tsukamoto S.

Abstract: Four new norditerpenes, taichunins A-D (1-4), were isolated from the fungus Aspergillus taichungensis (IBT 19404). Compound 1 has a new carbon framework. The absolute configurations were determined by the calculated ECD spectral method. Compound 1 was cytotoxic against HeLa cells with an IC50 value of 4.5 μM, whereas 2-4 were nontoxic at 50 μM.

CiteXplore: 30995043

DOI: 10.1021/acs.jnatprod.8b01032

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