Document Report Card

Basic Information

ID: ALA4330109

Journal: Bioorg Med Chem Lett

Title: Parallel synthesis of a bis-triazoles library as psammaplin A analogues: A new wave of antibiofilm compounds?

Authors: Andjouh S, Blache Y.

Abstract: Synthesis of psammaplin A analogues is described. Screening for antibiofilm activity of the targeted library afford some interesting elements in terms of structure-activity relationships. Some compounds exhibited EC50 in the range of ampicillin against three strains of gramnegative bacteria without toxic effect.

CiteXplore: 30600205

DOI: 10.1016/j.bmcl.2018.12.047