Document Report Card

ID: ALA4368861

Journal: Medchemcomm

Title: Screening of the Pathogen Box reveals new starting points for anti-trypanosomal drug discovery.

Authors: Veale CGL, Hoppe HC.

Abstract: This study aimed to uncover new starting points for anti-trypansomal drug discovery through the screening of the Pathogen Box against Trypanosoma brucei brucei. Our study identified compounds 35, 39, 46, 53 and 56 whose activity and selectivity highlighted them as promising candidates with potential for further study and optimisation.

CiteXplore: 30647879

DOI: 10.1039/C8MD00319J