Document Report Card

ID: ALA4373668

Journal: Medchemcomm

Title: Bivalent AMPA receptor positive allosteric modulators of the bis(pyrimidine) series.

Authors: Nazarova AA, Sedenkova KN, Karlov DS, Lavrov MI, Grishin YK, Kuznetsova TS, Zamoyski VL, Grigoriev VV, Averina EB, Palyulin VA.

Abstract: The first example of a novel class of AMPA receptor positive allosteric modulators of the bis(pyrimidine) series having a hydroquinone linker has been obtained and showed a potency to increase kainate-induced currents at subnanomolar concentrations.

CiteXplore: 31803402

DOI: 10.1039/C9MD00262F