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ID: ALA4414677
Journal: J Nat Prod
Title: Albanitriles A-G: Antiprotozoal Polyacetylene Nitriles from a Mycale Marine Sponge.
Authors: Sala S, Fromont J, Gomez O, Vuong D, Lacey E, Flematti GR.
Abstract: Seven new nitrile-bearing polyacetylenes, named albanitriles A-G, were isolated from a marine sponge of the Mycale genus (Order: Poecilosclerida, Family: Mycalidae) collected near Albany, Western Australia. Structural elucidation was achieved using a combination of high-resolution mass spectrometry and ultraviolet/visible, infrared, and nuclear magnetic resonance spectroscopy. The compounds were found to possess moderate activity against Giardia duodenalis when compared to a metronidazole positive control.
CiteXplore: 31833368