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ID: ALA4477157
Journal: J Nat Prod
Title: Iridoid Glucosides and Diterpenoids from Caryopteris glutinosa.
Authors: Luo G, Ye Q, Du B, Wang F, Zhang GL, Luo Y.
Abstract: Five new iridoid glucoside derivatives (1-5), three new diterpenoids (7, 12, and 15), and 11 known compounds were isolated from the aqueous EtOH extract of Caryopteris glutinosa. Cell-based estrogen biosynthesis assays indicated that caryopteriside C (3) and caryopterisoid B (12) promote the biosynthesis of estrogen E2, with EC50 values of 11.1 and 8.0 μM, respectively, in human ovarian granulosa-like KGN cells via upregulating the expression of aromatase.
CiteXplore: 26900877