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ID: ALA4477161

Journal: J Nat Prod

Title: Facile Synthesis of Natural Alkoxynaphthalene Analogues from Plant Alkoxybenzenes.

Authors: Tsyganov DV, Krayushkin MM, Konyushkin LD, Strelenko YA, Semenova MN, Semenov VV.

Abstract: Analogues of the bioactive natural alkoxynaphthalene pycnanthulignene D were synthesized by an efficient method. The starting plant allylalkoxybenzenes (1) are easily available from the plant essential oils of sassafras, dill, and parsley. The target 1-arylalkoxynaphthalenes (5) exhibited antiproliferative activity in a phenotypic sea urchin embryo assay.

CiteXplore: 26910798

DOI: 10.1021/acs.jnatprod.5b01007