Document Report Card
Basic Information
ID: ALA4507293
Title: Data for DCP probe THPP-1
Authors: SGC Frankfurt
Abstract: SGC Frankfurt donated chemical probe project: THPP-1 was donated by MSD. Website: https://www.sgc-ffm.uni-frankfurt.de/#!specificprobeoverview/THPP-1. Control: THPP-1-NC. References: 1. Raheem, Izzat T, Michael J Breslin, Christine Fandozzi, Joy Fuerst, Nicole Hill, Sarah Huszar, Monika Kandebo, Somang H Kim, Bennett Ma, Georgia McGaughey, John J Renger, John D Schreier, Sujata Sharma, Sean Smith, Jason Uslaner, Youwei Yan, Paul J Coleman, and Christopher D Cox. 2012. ‘Discovery of Tetrahydropyridopyrimidine Phosphodiesterase 10A Inhibitors for the Treatment of Schizophrenia’. Bioorganic & Medicinal Chemistry Letters 22(18):5903–8. PMID: 22892116. 2. Smith, Sean M, Jason M Uslaner, Christopher D Cox, Sarah L Huszar, Christopher E Cannon, Joshua D Vardigan, Donnie Eddins, Dawn M Toolan, Monika Kandebo, Lihang Yao, Izzat T Raheem, John D Schreier, Michael J Breslin, Paul J Coleman, and John J Renger. 2013. ‘The Novel Phosphodiesterase 10A Inhibitor THPP-1 Has Antipsychotic-like Effects in Rat and Improves Cognition in Rat and Rhesus Monkey’. Neuropharmacology 64:215–23. PMID: 22750078 (Sec. paper).