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ID: ALA4507310
Title: Data for DCP probe A-1211212
Authors: SGC Frankfurt
Abstract: SGC Frankfurt donated chemical probe project: A-1211212 was donated by Abbvie. Website: https://www.sgc-ffm.uni-frankfurt.de/#!specificprobeoverview/A-1211212. Control: A-1210227. References: 1. Leverson, Joel D, Darren C Phillips, Michael J Mitten, Erwin R Boghaert, Dolores Diaz, Stephen K Tahir, Lisa D Belmont, Paul Nimmer, Yu Xiao, Xiaoju Max Ma, Kym N Lowes, Peter Kovar, Jun Chen, Sha Jin, Morey Smith, John Xue, Haichao Zhang, Anatol Oleksijew, Terrance J Magoc, Kedar S Vaidya, Daniel H Albert, Jacqueline M Tarrant, Nghi La, Le Wang, Zhi-Fu Tao, Michael D Wendt, Deepak Sampath, Saul H Rosenberg, Chris Tse, David C S Huang, Wayne J Fairbrother, Steven W Elmore, and Andrew J Souers. 2015. ‘Exploiting Selective BCL-2 Family Inhibitors to Dissect Cell Survival Dependencies and Define Improved Strategies for Cancer Therapy’. Science Translational Medicine 7(279):279ra40. PMID: 25787766 (Secondary paper). 2. Weder, B., M. Mozaffari, L. Biedermann, C. Mamie, A. Moncsek, L. Wang, S. H. Clarke, G. Rogler, B. L. McRae, C. L. Graff, P. A. Ruiz, and M. Hausmann. 2018. ‘BCL-2 Levels Do Not Predict Azathioprine Treatment Response in Inflammatory Bowel Disease, but Inhibition Induces Lymphocyte Apoptosis and Ameliorates Colitis in Mice’. Clinical and Experimental Immunology 193(3):346–60. PMID: 29745420 (Secondary paper).