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ID: ALA4507311
Title: Data for DCP probe A-1155463
Authors: SGC Frankfurt
Abstract: SGC Frankfurt donated chemical probe project: A-1155463 was donated by Abbvie. Website: https://www.sgc-ffm.uni-frankfurt.de/#!specificprobeoverview/A-1155463. Control: A-1107969. References: 1. Tao, Zhi-Fu, Lisa Hasvold, Le Wang, Xilu Wang, Andrew M Petros, Chang H Park, Erwin R Boghaert, Nathaniel D Catron, Jun Chen, Peter M Colman, Peter E Czabotar, Kurt Deshayes, Wayne J Fairbrother, John A Flygare, Sarah G Hymowitz, Sha Jin, Russell A Judge, Michael F T Koehler, Peter J Kovar, Guillaume Lessene, Michael J Mitten, Chudi O Ndubaku, Paul Nimmer, Hans E Purkey, Anatol Oleksijew, Darren C Phillips, Brad E Sleebs, Brian J Smith, Morey L Smith, Stephen K Tahir, Keith G Watson, Yu Xiao, John Xue, Haichao Zhang, Kerry Zobel, Saul H Rosenberg, Chris Tse, Joel D Leverson, Steven W Elmore, and Andrew J Souers. 2014. ‘Discovery of a Potent and Selective BCL-XL Inhibitor with in Vivo Activity’. ACS Medicinal Chemistry Letters 5(10):1088–93. PMID: 25313317. 2. Leverson, Joel D, Darren C Phillips, Michael J Mitten, Erwin R Boghaert, Dolores Diaz, Stephen K Tahir, Lisa D Belmont, Paul Nimmer, Yu Xiao, Xiaoju Max Ma, Kym N Lowes, Peter Kovar, Jun Chen, Sha Jin, Morey Smith, John Xue, Haichao Zhang, Anatol Oleksijew, Terrance J Magoc, Kedar S Vaidya, Daniel H Albert, Jacqueline M Tarrant, Nghi La, Le Wang, Zhi-Fu Tao, Michael D Wendt, Deepak Sampath, Saul H Rosenberg, Chris Tse, David C S Huang, Wayne J Fairbrother, Steven W Elmore, and Andrew J Souers. 2015. ‘Exploiting Selective BCL-2 Family Inhibitors to Dissect Cell Survival Dependencies and Define Improved Strategies for Cancer Therapy’. Science Translational Medicine 7(279):279ra40. PMID: 25787766. 3. Bulanova, Daria, Aleksandr Ianevski, Andrii Bugai, Yevhen Akimov, Suvi Kuivanen, Henrik Paavilainen, Laura Kakkola, Jatin Nandania, Laura Turunen, Tiina Ohman, Hanna Ala-Hongisto, Hanna M Pesonen, Marika S Kuisma, Anni Honkimaa, Emma L Walton, Valentyn Oksenych, Martina B Lorey, Dmitry Guschin, Jungmin Shim, Jinhee Kim, Thoa T Than, So Young Chang, Veijo Hukkanen, Evgeny Kulesskiy, Varpu S Marjomaki, Ilkka Julkunen, Tuula A Nyman, Sampsa Matikainen, Jani S Saarela, Famara Sane, Didier Hober, Gülsah Gabriel, Jef K De Brabander, Miika Martikainen, Marc P Windisch, Ji-Young Min, Roberto Bruzzone, Tero Aittokallio, Markus Vähä-Koskela, Olli Vapalahti, Arto Pulk, Vidya Velagapudi, and Denis E Kainov. 2017. ‘Antiviral Properties of Chemical Inhibitors of Cellular Anti-Apoptotic Bcl-2 Proteins’. Viruses 9(10). PMID: 28946654.