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ID: ALA4513101
Title: Naegleria gruberi Pathogen Box compounds screening
Authors: Sarink, M; Mykytyn, A; Tielens, A; van Hellemond, J
Abstract: 400 compounds from the Pathogen box were screened for inhibitory activity against Naegleria gruberi strain NEG-M. N. gruberi was grown in modified PYNFH medium in 96-wells plates. Compounds were added in 10 uM concentrations in triplicate wells. Optical density was measured daily, after 6 days area under the curve was calculated and compared to 0.1 % DMSO control.