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ID: ALA4619757
Journal: Bioorg Med Chem Lett
Title: Identification of new arylsulfide derivatives as anti-melanogenic agents in a zebrafish model.
Authors: Ahn SH, Hwang KS, Shin DS, Kim SS, Yang JY, Lee BH, Bae EJ, Choi BW, Bae MA, Ahn JH.
Abstract: A series of aryl sulfide derivatives was synthesized and evaluated for their anti-melanogenic activities. Several compounds, including 3e, 3i and 3q exhibited good anti-melanogenic activities. Among the derivatives, compound 3i showed good inhibitory effects against melanin synthesis and showed no toxicity in reconstituted human eye and skin tissues.
CiteXplore: 32386982