Basic Information
ID: ALA4842392
Journal: ACS Med Chem Lett
Title: Targeting KRAS Mutant Protein Inhibitor for Potential Treatment in Cancer.
Authors: Kargbo RB.
Abstract: In targeted protein degradation of kinases, key discoveries have been made specifically involving selective kinase degradation. Structural and biophysical studies on the ternary complex formation have provided a clear understanding of the basis for achieving degradation selectivity which is important in guiding the design of efficient and selective protein degraders.
CiteXplore: 34795848
DOI: 10.1021/acsmedchemlett.1c00496
Patent ID: ┄
Associated Items: Associated Bioactivities Associated Assays Associated Compounds Associated Targets