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ID: ALA5030569
Journal: ACS Med Chem Lett
Title: Cyclic ADP Ribose Hydrolase (CD38) Inhibitors.
Authors: Blass BE.
Abstract: The COVID pandemic has evidenced how vulnerable we are to emerging infectious diseases and how short our current armamentarium is. Flavivirus, single stranded RNA viruses transmitted by arthropods, are considered a global health challenge. No drugs to treat these infections have been approved. In this Viewpoint, we analyze the advantages and disadvantages of two different, but probably also complementary, therapeutic approaches: virus-targeting antivirals and host-targeting drugs.
CiteXplore: 35059114