Bifunctional Compounds as SMARCA2 Degraders for Treating Cancer.

Basic Information

ID: ALA5034043

Journal: ACS Med Chem Lett

Title: Bifunctional Compounds as SMARCA2 Degraders for Treating Cancer.

Authors: Sabnis RW.

Abstract: The COVID pandemic has evidenced how vulnerable we are to emerging infectious diseases and how short our current armamentarium is. Flavivirus, single stranded RNA viruses transmitted by arthropods, are considered a global health challenge. No drugs to treat these infections have been approved. In this Viewpoint, we analyze the advantages and disadvantages of two different, but probably also complementary, therapeutic approaches: virus-targeting antivirals and host-targeting drugs.

CiteXplore: 35059115

DOI: 10.1021/acsmedchemlett.1c00657

Patent ID: