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ID: ALA5058641
Title: Data for DCP probe TP-050
Authors: SGC Frankfurt
Abstract: SGC Frankfurt donated chemical probe project: TP-050 was donated by Takeda. Website: https://www.sgc-ffm.uni-frankfurt.de/#!specificprobeoverview/TP-050. Control: TP-050n. References: 1. Sakurai, Fumie, Takafumi Yukawa, Asato Kina, Masataka Murakami, Kazuaki Takami, Sachie Morimoto, Masaki Seto, Makoto Kamata, Tohru Yamashita, Kosuke Nakashima, Naohiro Narita, Ezio Bettini, Annarosa Ugolini, Mauro Corsi, and Tomoaki Hasui. 2022. ‘Discovery of Pyrazolo[1,5-a]Pyrazin-4-Ones as Potent and Brain Penetrant GluN2A-Selective Positive Allosteric Modulators Reducing AMPA Receptor Binding Activity’. Bioorganic & Medicinal Chemistry 56:116576. doi: 10.1016/j.bmc.2021.116576. PMID: 35051811 (Compound (R)-9, control (S)-9).