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ID: ALA5120753

Journal: Bioorg Med Chem

Title: Isolation and biological activity of azocine and azocane alkaloids.

Authors: Lee S, Sperry J.

Abstract: Thousands of known alkaloids contain a nitrogen (N) heterocycle. While five-, six- and seven-membered N-heterocycles (ie: pyrroles, imidazoles, indoles, pyridines and azepines and their saturated variants) are common, those with an eight-membered N-heterocycle are comparatively rare. This review discusses the structure and bioactivity of alkaloids that contain an azocine (or saturated azocane) ring, and the array of sources whence they originate.

CiteXplore: 34923389

DOI: 10.1016/j.bmc.2021.116560