Basic Information
ID: ALA5226384
Journal: J Nat Prod
Title: Total Syntheses, Absolute Configurations, and Cytotoxicity Evaluation of Ugonstilbenes A, B, and C from the Rhizomes of Helminthostachys zeylanica.
Authors: Lin CT, Yang YH, Cheng JJ, Don MJ.
Abstract: This study describes the first and efficient syntheses of the naturally occurring ugonstilbenes A, B, and C. The stilbene skeleton was prepared using the Horner-Wadsworth-Emmons reaction. On the basis of their specific rotations, the absolute configurations of ugonstilbenes A and C were both determined to be R, while the absolute configuration of ugonstilbene B was determined as 4aS,9aR. The synthesized compounds showed cytotoxic activities against selected human cancer cell lines.
CiteXplore: 36691388
DOI: 10.1021/acs.jnatprod.2c00919
Patent ID: ┄
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