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ID: ALA5230137

Journal: Eur J Med Chem

Title: 4-(3H)-quinazolinones N-3 substituted with a five membered heterocycle: A promising scaffold towards bioactive molecules.

Authors: Plescia F, Maggio B, Daidone G, Raffa D.

Abstract: The quinazolinone nucleus represents, among the class of fused heterocycles, a very important scaffold to obtain molecules with biological activities. A review of literature revealed how such kind of fused heterocycles, coming from natural or synthetic source, are associated with a wide range of biological activities. This review is mainly directed towards the 4-(3H)-quinazolinones N-3 substituted with a five membered heterocycle in which all the possible combinations of nitrogen, sulfur and oxygen atoms are present.

CiteXplore: 33309162

DOI: 10.1016/j.ejmech.2020.113070