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ID: ALA5252512
Journal: J Med Chem
Title: Recent Progress in the Development of HIV-1 Protease Inhibitors for the Treatment of HIV/AIDS.
Authors: Ghosh AK, Osswald HL, Prato G.
Abstract: HIV-1 protease inhibitors continue to play an important role in the treatment of HIV/AIDS, transforming this deadly ailment into a more manageable chronic infection. Over the years, intensive research has led to a variety of approved protease inhibitors for the treatment of HIV/AIDS. In this review, we outline current drug design and medicinal chemistry efforts toward the development of next-generation protease inhibitors beyond the currently approved drugs.
CiteXplore: 26799988