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Lethal(3)malignant brain tumor-like protein 1

Name And Classification

ID:  ALA1287622

Type:  SINGLE PROTEIN

Synonyms:   H-l(3)mbt | H-l(3)mbt protein | KIAA0681 | L(3)mbt protein homolog | L(3)mbt-like | L3MBT | L3MBTL | L3MBTL1 | L3MBTL1 | Lethal(3)malignant brain tumor-like protein 1

Organism:  Homo sapiens

Species Group:  Homo sapiens

Protein Target Classification:   Epigenetic regulator / Reader / Methyl-lysine/arginine binding protein / MBT domain

Target Components

DescriptionRelationshipAccession
Lethal(3)malignant brain tumor-like protein 1PROTEINQ9Y468

Associated Active Ligands

  1. Tetrahydrouridine
    ALA1235760

    Name:
    SID24802552

    Mol. Formula:
    C18H21ClN6O2

    M.W.:
    388.86

    Type:
    Small molecule

    AlogP:
    0.54

    Polar Surface Area:
    77.09

    HBA:
    8

    HBD:
    1

    #RO5 Violations:
    0

    #Rotatable Bonds:
    3

    Passes Ro3:
    N

    QED Weighted:
    0.71

    DETAILS
  2. Tetrahydrouridine
    ALA1235966

    Name:
    SID56463135

    Mol. Formula:
    C19H21NO4

    M.W.:
    327.38

    Type:
    Small molecule

    AlogP:
    2.77

    Polar Surface Area:
    62.16

    HBA:
    5

    HBD:
    2

    #RO5 Violations:
    0

    #Rotatable Bonds:
    2

    Passes Ro3:
    N

    QED Weighted:
    0.89

    DETAILS
  3. Tetrahydrouridine
    ALA1299902

    Name:
    SID3713856

    Mol. Formula:
    C16H16N4O4S2

    M.W.:
    392.46

    Type:
    Small molecule

    AlogP:
    0.84

    Polar Surface Area:
    101.37

    HBA:
    8

    HBD:
    1

    #RO5 Violations:
    0

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.57

    DETAILS
  4. Tetrahydrouridine
    ALA1300382

    Name:
    SID4257000

    Mol. Formula:
    C15H16ClNO3

    M.W.:
    293.75

    Type:
    Small molecule

    AlogP:
    2.54

    Polar Surface Area:
    66.40

    HBA:
    2

    HBD:
    2

    #RO5 Violations:
    0

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.90

    DETAILS
  5. Tetrahydrouridine
    ALA1300679

    Name:
    SID14738298

    Mol. Formula:
    C16H17NO4S

    M.W.:
    319.38

    Type:
    Small molecule

    AlogP:
    3.09

    Polar Surface Area:
    75.63

    HBA:
    4

    HBD:
    2

    #RO5 Violations:
    0

    #Rotatable Bonds:
    7

    Passes Ro3:
    N

    QED Weighted:
    0.82

    DETAILS
  6. Tetrahydrouridine
    ALA1300993

    Name:
    SID24803752

    Mol. Formula:
    C17H20BrNO

    M.W.:
    334.26

    Type:
    Small molecule

    AlogP:
    1.64

    Polar Surface Area:
    20.23

    HBA:
    1

    HBD:
    1

    #RO5 Violations:
    0

    #Rotatable Bonds:
    2

    Passes Ro3:
    Y

    QED Weighted:
    0.63

    DETAILS
  7. Tetrahydrouridine
    ALA1301521

    Name:
    SID17413842

    Mol. Formula:
    C17H18N2O4

    M.W.:
    314.34

    Type:
    Small molecule

    AlogP:
    3.70

    Polar Surface Area:
    81.47

    HBA:
    4

    HBD:
    1

    #RO5 Violations:
    0

    #Rotatable Bonds:
    7

    Passes Ro3:
    N

    QED Weighted:
    0.48

    DETAILS
  8. Tetrahydrouridine
    ALA1301677

    Name:
    SID17507872

    Mol. Formula:
    C21H22N4O3

    M.W.:
    378.43

    Type:
    Small molecule

    AlogP:
    2.76

    Polar Surface Area:
    89.16

    HBA:
    5

    HBD:
    2

    #RO5 Violations:
    0

    #Rotatable Bonds:
    8

    Passes Ro3:
    N

    QED Weighted:
    0.47

    DETAILS
  9. Tetrahydrouridine
    ALA1302540

    Name:
    SID7966119

    Mol. Formula:
    C17H15ClFN5

    M.W.:
    343.79

    Type:
    Small molecule

    AlogP:
    3.80

    Polar Surface Area:
    68.76

    HBA:
    5

    HBD:
    2

    #RO5 Violations:
    0

    #Rotatable Bonds:
    2

    Passes Ro3:
    N

    QED Weighted:
    0.74

    DETAILS
  10. Tetrahydrouridine
    ALA1302638

    Name:
    SID24817304

    Mol. Formula:
    C13H8Cl2O3S

    M.W.:
    315.18

    Type:
    Small molecule

    AlogP:
    3.91

    Polar Surface Area:
    54.37

    HBA:
    3

    HBD:
    1

    #RO5 Violations:
    0

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.87

    DETAILS