Ataxin-2

Name And Classification

ID:  ALA1795085

Type:  SINGLE PROTEIN

Synonyms:   Ataxin-2 | ATX2 | ATXN2 | SCA2 | Spinocerebellar ataxia type 2 protein | TNRC13 | Trinucleotide repeat-containing gene 13 protein

Organism:  Homo sapiens

Species Group:  Homo sapiens

Protein Target Classification:   Unclassified protein

Target Components

DescriptionRelationshipAccession
Ataxin-2PROTEINQ99700

Associated Active Ligands

  1. Tetrahydrouridine
    ALA283206

    Name:
    SID124881900

    Mol. Formula:
    C27H26N2O3

    M.W.:
    426.52

    Type:
    Small molecule

    AlogP:
    4.60

    Polar Surface Area:
    43.70

    HBA:
    5

    HBD:
    0

    #RO5 Violations:
    0

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.45

    DETAILS
  2. Tetrahydrouridine
    ALA356136

    Name:
    SID49641972

    Mol. Formula:
    C19H20FNO

    M.W.:
    297.37

    Type:
    Small molecule

    AlogP:
    3.92

    Polar Surface Area:
    20.31

    HBA:
    2

    HBD:
    0

    #RO5 Violations:
    0

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.80

    DETAILS
  3. Tetrahydrouridine
    ALA1310731

    Name:
    SID49827643

    Mol. Formula:
    C21H21F3N4O5

    M.W.:
    466.42

    Type:
    Small molecule

    AlogP:
    3.16

    Polar Surface Area:
    105.02

    HBA:
    6

    HBD:
    1

    #RO5 Violations:
    0

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.52

    DETAILS
  4. Tetrahydrouridine
    ALA1327918

    Name:
    SID7976956

    Mol. Formula:
    C10H10Cl2O4S

    M.W.:
    297.16

    Type:
    Small molecule

    AlogP:
    2.33

    Polar Surface Area:
    60.44

    HBA:
    4

    HBD:
    0

    #RO5 Violations:
    0

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.80

    DETAILS
  5. Tetrahydrouridine
    ALA1358565

    Name:
    SID90340616

    Mol. Formula:
    C20H24N2O2

    M.W.:
    324.42

    Type:
    Small molecule

    AlogP:
    3.17

    Polar Surface Area:
    45.59

    HBA:
    4

    HBD:
    1

    #RO5 Violations:
    0

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.88

    DETAILS
  6. Tetrahydrouridine
    ALA1403731

    Name:
    SID26730667

    Mol. Formula:
    C21H21N3O4

    M.W.:
    379.42

    Type:
    Small molecule

    AlogP:
    1.44

    Polar Surface Area:
    78.95

    HBA:
    5

    HBD:
    1

    #RO5 Violations:
    0

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.80

    DETAILS
  7. Tetrahydrouridine
    ALA1412229

    Name:
    SID14722529

    Mol. Formula:
    C21H30N2O3S

    M.W.:
    390.55

    Type:
    Small molecule

    AlogP:
    3.40

    Polar Surface Area:
    66.48

    HBA:
    3

    HBD:
    1

    #RO5 Violations:
    0

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.76

    DETAILS
  8. Tetrahydrouridine
    ALA1419344

    Name:
    SID24807796

    Mol. Formula:
    C20H24N2O4S

    M.W.:
    388.49

    Type:
    Small molecule

    AlogP:
    3.45

    Polar Surface Area:
    76.66

    HBA:
    5

    HBD:
    2

    #RO5 Violations:
    0

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.74

    DETAILS
  9. Tetrahydrouridine
    ALA1443862

    Name:
    SID24789196

    Mol. Formula:
    C20H19N3O6

    M.W.:
    397.39

    Type:
    Small molecule

    AlogP:
    2.81

    Polar Surface Area:
    111.01

    HBA:
    6

    HBD:
    1

    #RO5 Violations:
    0

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.63

    DETAILS
  10. Tetrahydrouridine
    ALA1486279

    Name:
    SID17409595

    Mol. Formula:
    C16H12FN5O3

    M.W.:
    341.30

    Type:
    Small molecule

    AlogP:
    2.88

    Polar Surface Area:
    102.95

    HBA:
    6

    HBD:
    1

    #RO5 Violations:
    0

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.58

    DETAILS