Serotonin 3a (5-HT3a) receptor
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ID: ALA1899
Type: SINGLE PROTEIN
Synonyms: 5-HT-3 | 5-HT3-A | 5-HT3A | 5-HT3R | 5-hydroxytryptamine receptor 3 | 5-hydroxytryptamine receptor 3A | 5HT3R | HTR3 | HTR3A | Serotonin receptor 3A | Serotonin-gated ion channel receptor
Organism: Homo sapiens
Species Group: Homo sapiens
Protein Target Classification: Ion channel / Ligand-gated ion channel / 5HT3 receptor
ALA ID | Relationship | Pref Name | Target Type |
---|---|---|---|
ALA4296091 | SUBSET OF | 5-hydroxytryptamine receptor 3A/3C | PROTEIN COMPLEX |
ALA2111332 | SUBSET OF | Serotonin 3 (5-HT3) receptor | PROTEIN COMPLEX |
ALA2096904 | SUBSET OF | Serotonin (5-HT) receptor | PROTEIN FAMILY |
ALA2094132 | SUBSET OF | Serotonin 3 (5-HT3) receptor | PROTEIN COMPLEX GROUP |
ALA4296087 | SUBSET OF | 5-hydroxytryptamine receptor 3A/3E | PROTEIN COMPLEX |
Description | Relationship | Accession |
---|---|---|
5-hydroxytryptamine receptor 3A | PROTEIN | P46098 |
Name:
4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-((S)-methoxy)-benzamide
Mol. Formula:
C15H20ClN3O2
M.W.:
309.80
Type:
Small molecule
AlogP:
1.75
Polar Surface Area:
67.59
HBA:
4
HBD:
2
#RO5 Violations:
0
#Rotatable Bonds:
3
Passes Ro3:
N
QED Weighted:
0.83
Name:
2-(5-Methyl-1H-imidazol-4-ylmethyl)-4-phenyl-thiazole
Mol. Formula:
C14H13N3S
M.W.:
255.35
Type:
Small molecule
AlogP:
3.43
Polar Surface Area:
41.57
HBA:
3
HBD:
1
#RO5 Violations:
0
#Rotatable Bonds:
3
Passes Ro3:
N
QED Weighted:
0.78
Name:
3-[2-(5-Methyl-1H-imidazol-4-ylmethyl)-thiazol-4-yl]-1H-indole
Mol. Formula:
C16H14N4S
M.W.:
294.38
Type:
Small molecule
AlogP:
3.91
Polar Surface Area:
57.36
HBA:
3
HBD:
2
#RO5 Violations:
0
#Rotatable Bonds:
3
Passes Ro3:
N
QED Weighted:
0.60
Name:
1-(4-Methyl-benzyl)-2-piperazin-1-yl-1H-benzoimidazole
Mol. Formula:
C19H22N4
M.W.:
306.41
Type:
Small molecule
AlogP:
2.80
Polar Surface Area:
33.09
HBA:
4
HBD:
1
#RO5 Violations:
0
#Rotatable Bonds:
3
Passes Ro3:
N
QED Weighted:
0.81
Name:
1-(4-Methoxy-benzyl)-2-piperazin-1-yl-1H-benzoimidazole
Mol. Formula:
C19H22N4O
M.W.:
322.41
Type:
Small molecule
AlogP:
2.50
Polar Surface Area:
42.32
HBA:
5
HBD:
1
#RO5 Violations:
0
#Rotatable Bonds:
4
Passes Ro3:
N
QED Weighted:
0.80
Name:
1-(4-Fluoro-benzyl)-2-piperazin-1-yl-1H-benzoimidazole
Mol. Formula:
C18H19FN4
M.W.:
310.38
Type:
Small molecule
AlogP:
2.63
Polar Surface Area:
33.09
HBA:
4
HBD:
1
#RO5 Violations:
0
#Rotatable Bonds:
3
Passes Ro3:
N
QED Weighted:
0.81
Name:
1-(3-Phenyl-propyl)-2-piperazin-1-yl-1H-benzoimidazole
Mol. Formula:
C20H24N4
M.W.:
320.44
Type:
Small molecule
AlogP:
3.08
Polar Surface Area:
33.09
HBA:
4
HBD:
1
#RO5 Violations:
0
#Rotatable Bonds:
5
Passes Ro3:
N
QED Weighted:
0.78
Name:
1-Naphthalen-2-ylmethyl-2-piperazin-1-yl-1H-benzoimidazole
Mol. Formula:
C22H22N4
M.W.:
342.45
Type:
Small molecule
AlogP:
3.65
Polar Surface Area:
33.09
HBA:
4
HBD:
1
#RO5 Violations:
0
#Rotatable Bonds:
3
Passes Ro3:
N
QED Weighted:
0.62