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Proton-coupled amino acid transporter 1

Name And Classification

ID:  ALA1914279

Type:  SINGLE PROTEIN

Synonyms:   hPAT1 | PAT1 | Proton-coupled amino acid transporter 1 | Proton/amino acid transporter 1 | SLC36A1 | Solute carrier family 36 member 1 | Synonyms=PAT1

Organism:  Homo sapiens

Species Group:  Homo sapiens

Protein Target Classification:   Transporter / Electrochemical transporter / SLC superfamily of solute carriers / SLC36 family of proton-coupled amino acid transporters

Target Components

DescriptionRelationshipAccession
Proton-coupled amino acid transporter 1PROTEINQ7Z2H8

Associated Active Ligands

  1. Tetrahydrouridine
    ALA1229563

    Name:
    cis-4-Hydroxy-D-proline

    Mol. Formula:
    C5H9NO3

    M.W.:
    131.13

    Type:
    Small molecule

    AlogP:
    -1.21

    Polar Surface Area:
    69.56

    HBA:
    3

    HBD:
    3

    #RO5 Violations:
    0

    #Rotatable Bonds:
    1

    Passes Ro3:
    N

    QED Weighted:
    0.42

    DETAILS
  2. Tetrahydrouridine
    ALA1230782

    Name:
    L-alpha-Aminobutyric acid

    Mol. Formula:
    C4H9NO2

    M.W.:
    103.12

    Type:
    Small molecule

    AlogP:
    -0.19

    Polar Surface Area:
    63.32

    HBA:
    2

    HBD:
    2

    #RO5 Violations:
    0

    #Rotatable Bonds:
    2

    Passes Ro3:
    N

    QED Weighted:
    0.51

    DETAILS
  3. Tetrahydrouridine
    ALA1230906

    Name:
    alpha-Aminoisobutyric acid

    Mol. Formula:
    C4H9NO2

    M.W.:
    103.12

    Type:
    Small molecule

    AlogP:
    -0.19

    Polar Surface Area:
    63.32

    HBA:
    2

    HBD:
    2

    #RO5 Violations:
    0

    #Rotatable Bonds:
    1

    Passes Ro3:
    N

    QED Weighted:
    0.48

    DETAILS
  4. Tetrahydrouridine
    ALA1231898

    Name:
    D-Pipecolic acid

    Mol. Formula:
    C6H11NO2

    M.W.:
    129.16

    Type:
    Small molecule

    AlogP:
    0.21

    Polar Surface Area:
    49.33

    HBA:
    2

    HBD:
    2

    #RO5 Violations:
    0

    #Rotatable Bonds:
    1

    Passes Ro3:
    Y

    QED Weighted:
    0.53

    DETAILS
  5. Tetrahydrouridine
    ALA1233466

    Name:
    trans-3-Hydroxy-L-proline

    Mol. Formula:
    C5H9NO3

    M.W.:
    131.13

    Type:
    Small molecule

    AlogP:
    -1.21

    Polar Surface Area:
    69.56

    HBA:
    3

    HBD:
    3

    #RO5 Violations:
    0

    #Rotatable Bonds:
    1

    Passes Ro3:
    N

    QED Weighted:
    0.42

    DETAILS
  6. Tetrahydrouridine
    ALA1233477

    Name:
    cis-4-Hydroxy-L-proline

    Mol. Formula:
    C5H9NO3

    M.W.:
    131.13

    Type:
    Small molecule

    AlogP:
    -1.21

    Polar Surface Area:
    69.56

    HBA:
    3

    HBD:
    3

    #RO5 Violations:
    0

    #Rotatable Bonds:
    1

    Passes Ro3:
    N

    QED Weighted:
    0.42

    DETAILS
  7. Tetrahydrouridine
    ALA1233584

    Name:
    L-Isoleucine

    Mol. Formula:
    C6H13NO2

    M.W.:
    131.18

    Type:
    Small molecule

    AlogP:
    0.44

    Polar Surface Area:
    63.32

    HBA:
    2

    HBD:
    2

    #RO5 Violations:
    0

    #Rotatable Bonds:
    3

    Passes Ro3:
    N

    QED Weighted:
    0.58

    DETAILS
  8. Tetrahydrouridine
    ALA1234201

    Name:
    N-Methyl-L-alanine

    Mol. Formula:
    C4H9NO2

    M.W.:
    103.12

    Type:
    Small molecule

    AlogP:
    -0.32

    Polar Surface Area:
    49.33

    HBA:
    2

    HBD:
    2

    #RO5 Violations:
    0

    #Rotatable Bonds:
    2

    Passes Ro3:
    Y

    QED Weighted:
    0.50

    DETAILS
  9. Tetrahydrouridine
    ALA1916078

    Name:
    Thiazolidine

    Mol. Formula:
    C3H7NS

    M.W.:
    89.16

    Type:
    Small molecule

    AlogP:
    0.28

    Polar Surface Area:
    12.03

    HBA:
    2

    HBD:
    1

    #RO5 Violations:
    0

    #Rotatable Bonds:
    0

    Passes Ro3:
    Y

    QED Weighted:
    0.46

    DETAILS
  10. Tetrahydrouridine
    ALA1916079

    Name:
    N-Methylaminoisobutyric acid

    Mol. Formula:
    C5H11NO2

    M.W.:
    117.15

    Type:
    Small molecule

    AlogP:
    0.07

    Polar Surface Area:
    49.33

    HBA:
    2

    HBD:
    2

    #RO5 Violations:
    0

    #Rotatable Bonds:
    2

    Passes Ro3:
    Y

    QED Weighted:
    0.54

    DETAILS