Thyroid stimulating hormone receptor
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ID: ALA1963
Type: SINGLE PROTEIN
Synonyms: LGR3 | Thyroid-stimulating hormone receptor | Thyrotropin receptor | TSH-R | TSHR
Organism: Homo sapiens
Species Group: Homo sapiens
Protein Target Classification: Membrane receptor / Family A G protein-coupled receptor / Peptide receptor (family A GPCR) / Glycohormone receptor / Glycohormone receptor
Description | Relationship | Accession |
---|---|---|
Thyrotropin receptor | PROTEIN | P16473 |
Name | Specifications | Species reactivity | species | Application | View Details |
---|
Name:
N-tert-butyl-5-amino-4-(3-methoxyphenyl)-2-(methylthio)thieno[2,3-d]pyrimidine-6-carboxamide
Mol. Formula:
C19H22N4O2S2
M.W.:
402.55
Type:
Small molecule
AlogP:
4.20
Polar Surface Area:
90.13
HBA:
7
HBD:
2
#RO5 Violations:
0
#Rotatable Bonds:
4
Passes Ro3:
N
QED Weighted:
0.50
Name:
N'-boc-5-amino-4-(3-methoxyphenyl)-2-(methylthio)thieno-[2,3-d]pyrimidine-6-carbohydrazide
Mol. Formula:
C20H23N5O4S2
M.W.:
461.57
Type:
Small molecule
AlogP:
3.84
Polar Surface Area:
128.46
HBA:
9
HBD:
3
#RO5 Violations:
0
#Rotatable Bonds:
4
Passes Ro3:
N
QED Weighted:
0.30
Name:
N-tert-butyl-5-amino-4-(3-hydroxyphenyl)-2-(methylthio)thieno[2,3-d]pyrimidine-6-carboxamide
Mol. Formula:
C18H20N4O2S2
M.W.:
388.52
Type:
Small molecule
AlogP:
3.90
Polar Surface Area:
101.13
HBA:
7
HBD:
3
#RO5 Violations:
0
#Rotatable Bonds:
3
Passes Ro3:
N
QED Weighted:
0.46