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Thyroid stimulating hormone receptor

Name And Classification

ID:  ALA1963

Type:  SINGLE PROTEIN

Synonyms:   LGR3 | Thyroid-stimulating hormone receptor | Thyrotropin receptor | TSH-R | TSHR

Organism:  Homo sapiens

Species Group:  Homo sapiens

Protein Target Classification:   Membrane receptor / Family A G protein-coupled receptor / Peptide receptor (family A GPCR) / Glycohormone receptor / Glycohormone receptor

Target Components

DescriptionRelationshipAccession
Thyrotropin receptorPROTEINP16473

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details
Pamrevlumab (anti-CTGF)Human,Mouse,Rabbit,RatHuman
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
Expand
Recombinant CTGF AntibodyHuman,MouseRabbit
  • WB
Expand

Associated Active Ligands

  1. Tetrahydrouridine
    ALA466

    Name:
    SID17389546

    Mol. Formula:
    C16H16N4O8S

    M.W.:
    424.39

    Type:
    Small molecule

    AlogP:
    -0.54

    Polar Surface Area:
    173.76

    HBA:
    9

    HBD:
    3

    #RO5 Violations:
    0

    #Rotatable Bonds:
    7

    Passes Ro3:
    N

    QED Weighted:
    0.30

    DETAILS
  2. Tetrahydrouridine
    ALA16857

    Name:
    SID11111400

    Mol. Formula:
    C13H17N

    M.W.:
    187.29

    Type:
    Small molecule

    AlogP:
    2.18

    Polar Surface Area:
    3.24

    HBA:
    1

    HBD:
    0

    #RO5 Violations:
    0

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.65

    DETAILS
  3. Tetrahydrouridine
    ALA277076

    Name:
    SID7975554

    Mol. Formula:
    C12H16N6O4

    M.W.:
    308.30

    Type:
    Small molecule

    AlogP:
    -1.84

    Polar Surface Area:
    148.41

    HBA:
    9

    HBD:
    4

    #RO5 Violations:
    0

    #Rotatable Bonds:
    3

    Passes Ro3:
    N

    QED Weighted:
    0.52

    DETAILS
  4. Tetrahydrouridine
    ALA293349

    Name:
    SID11110886

    Mol. Formula:
    C18H25NO

    M.W.:
    271.40

    Type:
    Small molecule

    AlogP:
    3.33

    Polar Surface Area:
    23.47

    HBA:
    2

    HBD:
    1

    #RO5 Violations:
    0

    #Rotatable Bonds:
    2

    Passes Ro3:
    N

    QED Weighted:
    0.89

    DETAILS
  5. Tetrahydrouridine
    ALA292477

    Name:
    SID11113494

    Mol. Formula:
    C20H23N

    M.W.:
    277.41

    Type:
    Small molecule

    AlogP:
    4.17

    Polar Surface Area:
    3.24

    HBA:
    1

    HBD:
    0

    #RO5 Violations:
    0

    #Rotatable Bonds:
    2

    Passes Ro3:
    N

    QED Weighted:
    0.80

    DETAILS
  6. Tetrahydrouridine
    ALA1104

    Name:
    SID11111143

    Mol. Formula:
    C10H16NO+

    M.W.:
    166.24

    Type:
    Small molecule

    AlogP:
    1.98

    Polar Surface Area:
    20.23

    HBA:
    1

    HBD:
    1

    #RO5 Violations:
    0

    #Rotatable Bonds:
    2

    Passes Ro3:
    Y

    QED Weighted:
    0.67

    DETAILS
  7. Tetrahydrouridine
    ALA152299

    Name:
    SID17389489

    Mol. Formula:
    C14H14O

    M.W.:
    198.26

    Type:
    Small molecule

    AlogP:
    3.40

    Polar Surface Area:
    9.23

    HBA:
    1

    HBD:
    0

    #RO5 Violations:
    0

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.73

    DETAILS
  8. Tetrahydrouridine
    ALA211405

    Name:
    N-tert-butyl-5-amino-4-(3-methoxyphenyl)-2-(methylthio)thieno[2,3-d]pyrimidine-6-carboxamide

    Mol. Formula:
    C19H22N4O2S2

    M.W.:
    402.55

    Type:
    Small molecule

    AlogP:
    4.20

    Polar Surface Area:
    90.13

    HBA:
    7

    HBD:
    2

    #RO5 Violations:
    0

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.50

    DETAILS
  9. Tetrahydrouridine
    ALA211406

    Name:
    N'-boc-5-amino-4-(3-methoxyphenyl)-2-(methylthio)thieno-[2,3-d]pyrimidine-6-carbohydrazide

    Mol. Formula:
    C20H23N5O4S2

    M.W.:
    461.57

    Type:
    Small molecule

    AlogP:
    3.84

    Polar Surface Area:
    128.46

    HBA:
    9

    HBD:
    3

    #RO5 Violations:
    0

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.30

    DETAILS
  10. Tetrahydrouridine
    ALA378091

    Name:
    N-tert-butyl-5-amino-4-(3-hydroxyphenyl)-2-(methylthio)thieno[2,3-d]pyrimidine-6-carboxamide

    Mol. Formula:
    C18H20N4O2S2

    M.W.:
    388.52

    Type:
    Small molecule

    AlogP:
    3.90

    Polar Surface Area:
    101.13

    HBA:
    7

    HBD:
    3

    #RO5 Violations:
    0

    #Rotatable Bonds:
    3

    Passes Ro3:
    N

    QED Weighted:
    0.46

    DETAILS