ID: ALA1983
Type: SINGLE PROTEIN
Synonyms: 5-HT-1D | 5-HT-1D-alpha | 5-HT1D | 5-hydroxytryptamine receptor 1D | HTR1D | HTR1DA | HTRL | Serotonin 1D alpha receptor | Serotonin receptor 1D
Organism: Homo sapiens
Species Group: Homo sapiens
Protein Target Classification: Membrane receptor / Family A G protein-coupled receptor / Small molecule receptor (family A GPCR) / Monoamine receptor / Serotonin receptor
ALA ID | Relationship | Pref Name | Target Type |
---|---|---|---|
ALA4524122 | SUBSET OF | Serotonin 1 (5-HT1) receptor | PROTEIN FAMILY |
ALA2095230 | SUBSET OF | Serotonin 1 receptors; 5-HT1B & 5-HT1D | SELECTIVITY GROUP |
ALA2096904 | SUBSET OF | Serotonin (5-HT) receptor | PROTEIN FAMILY |
ALA4523960 | SUBSET OF | 5-HT1D/5-HT1F | SELECTIVITY GROUP |
Description | Relationship | Accession |
---|---|---|
5-hydroxytryptamine receptor 1D | PROTEIN | P28221 |
Name:
5-tert-Butyl-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1H-indole
Mol. Formula:
C18H26N2
M.W.:
270.42
Type:
Small molecule
AlogP:
4.10
Polar Surface Area:
19.03
HBA:
1
HBD:
1
#RO5 Violations:
0
#Rotatable Bonds:
2
Passes Ro3:
N
QED Weighted:
0.87
Name:
5-Methyl-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1H-indole
Mol. Formula:
C15H20N2
M.W.:
228.34
Type:
Small molecule
AlogP:
3.11
Polar Surface Area:
19.03
HBA:
1
HBD:
1
#RO5 Violations:
0
#Rotatable Bonds:
2
Passes Ro3:
N
QED Weighted:
0.84
Name:
5-Isopropyl-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1H-indole
Mol. Formula:
C17H24N2
M.W.:
256.39
Type:
Small molecule
AlogP:
3.93
Polar Surface Area:
19.03
HBA:
1
HBD:
1
#RO5 Violations:
0
#Rotatable Bonds:
3
Passes Ro3:
N
QED Weighted:
0.88
Name:
5-Ethyl-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1H-indole
Mol. Formula:
C16H22N2
M.W.:
242.37
Type:
Small molecule
AlogP:
3.37
Polar Surface Area:
19.03
HBA:
1
HBD:
1
#RO5 Violations:
0
#Rotatable Bonds:
3
Passes Ro3:
N
QED Weighted:
0.87
Name:
[2-(5-Isopropyl-1H-indol-3-yl)-ethyl]-dimethyl-amine
Mol. Formula:
C15H22N2
M.W.:
230.35
Type:
Small molecule
AlogP:
3.40
Polar Surface Area:
19.03
HBA:
1
HBD:
1
#RO5 Violations:
0
#Rotatable Bonds:
4
Passes Ro3:
N
QED Weighted:
0.85
Name:
Dimethyl-[2-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-ethyl]-amine
Mol. Formula:
C14H17N5
M.W.:
255.32
Type:
Small molecule
AlogP:
1.85
Polar Surface Area:
49.74
HBA:
4
HBD:
1
#RO5 Violations:
0
#Rotatable Bonds:
4
Passes Ro3:
N
QED Weighted:
0.77