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Glucagon receptor

Name And Classification

ID:  ALA1985

Type:  SINGLE PROTEIN

Synonyms:   GCGR | GL-R | Glucagon receptor

Organism:  Homo sapiens

Species Group:  Homo sapiens

Protein Target Classification:   Membrane receptor / Family B G protein-coupled receptor / Peptide receptor (family B GPCR) / Glucagon-like receptor / Glucagon receptor

Target Components

DescriptionRelationshipAccession
Glucagon receptorPROTEINP47871

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Active Ligands

  1. Tetrahydrouridine
    ALA278041

    Name:
    4-[4-(4-Fluoro-phenyl)-5-pyridin-4-yl-1H-imidazol-2-yl]-phenol

    Mol. Formula:
    C20H14FN3O

    M.W.:
    331.35

    Type:
    Small molecule

    AlogP:
    4.65

    Polar Surface Area:
    61.80

    HBA:
    3

    HBD:
    2

    #RO5 Violations:
    0

    #Rotatable Bonds:
    3

    Passes Ro3:
    N

    QED Weighted:
    0.57

    DETAILS
  2. Tetrahydrouridine
    ALA276063

    Name:
    4-[5-(4-Fluoro-phenyl)-2-(4-methoxy-phenyl)-3H-imidazol-4-yl]-pyridine

    Mol. Formula:
    C21H16FN3O

    M.W.:
    345.38

    Type:
    Small molecule

    AlogP:
    4.95

    Polar Surface Area:
    50.80

    HBA:
    3

    HBD:
    1

    #RO5 Violations:
    0

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.57

    DETAILS
  3. Tetrahydrouridine
    ALA17736

    Name:
    4-[4-(4-Fluoro-phenyl)-5-pyridin-4-yl-1H-imidazol-2-yl]-phenylamine

    Mol. Formula:
    C20H15FN4

    M.W.:
    330.37

    Type:
    Small molecule

    AlogP:
    4.53

    Polar Surface Area:
    67.59

    HBA:
    3

    HBD:
    2

    #RO5 Violations:
    0

    #Rotatable Bonds:
    3

    Passes Ro3:
    N

    QED Weighted:
    0.54

    DETAILS
  4. Tetrahydrouridine
    ALA17396

    Name:
    4-[4-(4-Fluoro-phenyl)-5-pyridin-4-yl-1H-imidazol-2-yl]-benzonitrile

    Mol. Formula:
    C21H13FN4

    M.W.:
    340.36

    Type:
    Small molecule

    AlogP:
    4.82

    Polar Surface Area:
    65.36

    HBA:
    3

    HBD:
    1

    #RO5 Violations:
    0

    #Rotatable Bonds:
    3

    Passes Ro3:
    N

    QED Weighted:
    0.58

    DETAILS
  5. Tetrahydrouridine
    ALA17370

    Name:
    4-[5-(4-Fluoro-phenyl)-2-(4-methylsulfanyl-phenyl)-3H-imidazol-4-yl]-pyridine

    Mol. Formula:
    C21H16FN3S

    M.W.:
    361.45

    Type:
    Small molecule

    AlogP:
    5.67

    Polar Surface Area:
    41.57

    HBA:
    3

    HBD:
    1

    #RO5 Violations:
    1

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.48

    DETAILS
  6. Tetrahydrouridine
    ALA416169

    Name:
    4-[5-(4-Fluoro-phenyl)-2-phenyl-3H-imidazol-4-yl]-pyridine

    Mol. Formula:
    C20H14FN3

    M.W.:
    315.35

    Type:
    Small molecule

    AlogP:
    4.94

    Polar Surface Area:
    41.57

    HBA:
    2

    HBD:
    1

    #RO5 Violations:
    0

    #Rotatable Bonds:
    3

    Passes Ro3:
    N

    QED Weighted:
    0.58

    DETAILS
  7. Tetrahydrouridine
    ALA17722

    Name:
    4-[4-(4-Fluoro-phenyl)-5-pyridin-4-yl-1H-imidazol-2-yl]-benzoic acid methyl ester

    Mol. Formula:
    C22H16FN3O2

    M.W.:
    373.39

    Type:
    Small molecule

    AlogP:
    4.73

    Polar Surface Area:
    67.87

    HBA:
    4

    HBD:
    1

    #RO5 Violations:
    0

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.53

    DETAILS
  8. Tetrahydrouridine
    ALA24616

    Name:
    [4-(4-Fluoro-phenyl)-2,6-diisopropyl-5-pentyl-pyridin-3-yl]-methanol

    Mol. Formula:
    C23H32FNO

    M.W.:
    357.51

    Type:
    Small molecule

    AlogP:
    6.36

    Polar Surface Area:
    33.12

    HBA:
    2

    HBD:
    1

    #RO5 Violations:
    1

    #Rotatable Bonds:
    8

    Passes Ro3:
    N

    QED Weighted:
    0.56

    DETAILS
  9. Tetrahydrouridine
    ALA24533

    Name:
    (2,6-Diisopropyl-4-naphthalen-1-yl-5-pentyl-pyridin-3-yl)-methanol

    Mol. Formula:
    C27H35NO

    M.W.:
    389.58

    Type:
    Small molecule

    AlogP:
    7.37

    Polar Surface Area:
    33.12

    HBA:
    2

    HBD:
    1

    #RO5 Violations:
    1

    #Rotatable Bonds:
    8

    Passes Ro3:
    N

    QED Weighted:
    0.41

    DETAILS
  10. Tetrahydrouridine
    ALA286555

    Name:
    [4-(3,4-Difluoro-phenyl)-2,6-diisopropyl-5-pentyl-pyridin-3-yl]-methanol

    Mol. Formula:
    C23H31F2NO

    M.W.:
    375.50

    Type:
    Small molecule

    AlogP:
    6.50

    Polar Surface Area:
    33.12

    HBA:
    2

    HBD:
    1

    #RO5 Violations:
    1

    #Rotatable Bonds:
    8

    Passes Ro3:
    N

    QED Weighted:
    0.53

    DETAILS