ID: ALA2034
Type: SINGLE PROTEIN
Synonyms: Glucocorticoid receptor | GRL | NR3C1 | Nuclear receptor subfamily 3 group C member 1
Organism: Homo sapiens
Species Group: Homo sapiens
Protein Target Classification: Transcription factor / Nuclear receptor / Nuclear hormone receptor subfamily 3 / Nuclear hormone receptor subfamily 3 group C / Nuclear hormone receptor subfamily 3 group C member 1
Description | Relationship | Accession |
---|---|---|
Glucocorticoid receptor | PROTEIN | P04150 |
Name:
5-Allyl-7-bromo-10-chloro-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysen-9-ol
Mol. Formula:
C22H21BrClNO2
M.W.:
446.77
Type:
Small molecule
AlogP:
7.09
Polar Surface Area:
41.49
HBA:
3
HBD:
2
#RO5 Violations:
1
#Rotatable Bonds:
2
Passes Ro3:
N
QED Weighted:
0.48
Name:
5-Allyl-10-chloro-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysen-9-ol
Mol. Formula:
C22H22ClNO2
M.W.:
367.88
Type:
Small molecule
AlogP:
6.33
Polar Surface Area:
41.49
HBA:
3
HBD:
2
#RO5 Violations:
1
#Rotatable Bonds:
2
Passes Ro3:
N
QED Weighted:
0.61
Name:
5-Allyl-10-allyloxy-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene
Mol. Formula:
C25H27NO2
M.W.:
373.50
Type:
Small molecule
AlogP:
6.54
Polar Surface Area:
30.49
HBA:
3
HBD:
1
#RO5 Violations:
1
#Rotatable Bonds:
5
Passes Ro3:
N
QED Weighted:
0.60
Name:
5-Allyl-10-methoxy-2,2,4-trimethyl-7-vinyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene
Mol. Formula:
C25H27NO2
M.W.:
373.50
Type:
Small molecule
AlogP:
6.62
Polar Surface Area:
30.49
HBA:
3
HBD:
1
#RO5 Violations:
1
#Rotatable Bonds:
4
Passes Ro3:
N
QED Weighted:
0.61
Name:
5-Allyl-10-difluoromethoxy-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene
Mol. Formula:
C23H23F2NO2
M.W.:
383.44
Type:
Small molecule
AlogP:
6.57
Polar Surface Area:
30.49
HBA:
3
HBD:
1
#RO5 Violations:
1
#Rotatable Bonds:
4
Passes Ro3:
N
QED Weighted:
0.61
Name:
5-Allyl-10-chloro-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene
Mol. Formula:
C22H22ClNO
M.W.:
351.88
Type:
Small molecule
AlogP:
6.62
Polar Surface Area:
21.26
HBA:
2
HBD:
1
#RO5 Violations:
1
#Rotatable Bonds:
2
Passes Ro3:
N
QED Weighted:
0.61
Name:
5-Allyl-10-ethoxy-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene
Mol. Formula:
C24H27NO2
M.W.:
361.49
Type:
Small molecule
AlogP:
6.37
Polar Surface Area:
30.49
HBA:
3
HBD:
1
#RO5 Violations:
1
#Rotatable Bonds:
4
Passes Ro3:
N
QED Weighted:
0.64
Name:
5-Allyl-9-chloro-10-methoxy-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene
Mol. Formula:
C23H24ClNO2
M.W.:
381.90
Type:
Small molecule
AlogP:
6.63
Polar Surface Area:
30.49
HBA:
3
HBD:
1
#RO5 Violations:
1
#Rotatable Bonds:
3
Passes Ro3:
N
QED Weighted:
0.60
Name:
5-Allyl-9-fluoro-10-methoxy-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene
Mol. Formula:
C23H24FNO2
M.W.:
365.45
Type:
Small molecule
AlogP:
6.12
Polar Surface Area:
30.49
HBA:
3
HBD:
1
#RO5 Violations:
1
#Rotatable Bonds:
3
Passes Ro3:
N
QED Weighted:
0.66
Name:
5-Allyl-10-methoxy-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene
Mol. Formula:
C23H25NO2
M.W.:
347.46
Type:
Small molecule
AlogP:
5.98
Polar Surface Area:
30.49
HBA:
3
HBD:
1
#RO5 Violations:
1
#Rotatable Bonds:
3
Passes Ro3:
N
QED Weighted:
0.69