ID: ALA2094116
Type: PROTEIN COMPLEX
Synonyms: 5-HT-3 | 5-HT3-A | 5-HT3A | 5-HT3R | 5-hydroxytryptamine receptor 3 | 5-hydroxytryptamine receptor 3A | 5ht3 | Htr3 | Htr3a | Serotonin receptor 3A | Serotonin-gated ion channel receptor
Organism: Rattus norvegicus
Species Group: Rattus norvegicus
Protein Target Classification: Ion channel / Ligand-gated ion channel / 5HT3 receptor
ALA ID | Relationship | Pref Name | Target Type |
---|---|---|---|
ALA2094123 | SUBSET OF | Serotonin (5-HT) receptor | PROTEIN FAMILY |
ALA2411 | SUPERSET OF | Serotonin 3a (5-HT3a) receptor | SINGLE PROTEIN |
Name | Specifications | Species reactivity | species | Application | View Details |
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Name:
2'-(5-methoxy-1-methyl-1H-indol-3-yl)-4'H-spiro[4-azabicyclo[2.2.2]octane-2,5'-[1,3]oxazole]
Mol. Formula:
C19H23N3O2
M.W.:
325.41
Type:
Small molecule
AlogP:
2.43
Polar Surface Area:
38.99
HBA:
5
HBD:
0
#RO5 Violations:
0
#Rotatable Bonds:
2
Passes Ro3:
N
QED Weighted:
0.85
Name:
1-methyl-3-(4'H-spiro[4-azabicyclo[2.2.2]octane-2,5'-[1,3]oxazol]-2'-yl)-1H-indol-5-amine
Mol. Formula:
C18H22N4O
M.W.:
310.40
Type:
Small molecule
AlogP:
2.00
Polar Surface Area:
55.78
HBA:
5
HBD:
1
#RO5 Violations:
0
#Rotatable Bonds:
1
Passes Ro3:
N
QED Weighted:
0.82
Name:
2'-(1-methyl-5-nitro-1H-indol-3-yl)-4'H-spiro[4-azabicyclo[2.2.2]octane-2,5'-[1,3]oxazole]
Mol. Formula:
C18H20N4O3
M.W.:
340.38
Type:
Small molecule
AlogP:
2.33
Polar Surface Area:
72.90
HBA:
6
HBD:
0
#RO5 Violations:
0
#Rotatable Bonds:
2
Passes Ro3:
N
QED Weighted:
0.62
Name:
2'-(1,5-dimethyl-1H-indol-3-yl)-4'H-spiro[4-azabicyclo[2.2.2]octane-2,5'-[1,3]oxazole]
Mol. Formula:
C19H23N3O
M.W.:
309.41
Type:
Small molecule
AlogP:
2.73
Polar Surface Area:
29.76
HBA:
4
HBD:
0
#RO5 Violations:
0
#Rotatable Bonds:
1
Passes Ro3:
N
QED Weighted:
0.81
Name:
8-Methyl-2-(1-methyl-1H-indol-3-yl)-1-oxa-3,8-diaza-spiro[4.5]dec-2-ene
Mol. Formula:
C17H21N3O
M.W.:
283.37
Type:
Small molecule
AlogP:
2.42
Polar Surface Area:
29.76
HBA:
4
HBD:
0
#RO5 Violations:
0
#Rotatable Bonds:
1
Passes Ro3:
N
QED Weighted:
0.80
Name:
1-methyl-3-(4'H-spiro[4-azabicyclo[2.2.2]octane-2,5'-[1,3]oxazol]-2'-yl)-1H-indol-5-ol
Mol. Formula:
C18H21N3O2
M.W.:
311.38
Type:
Small molecule
AlogP:
2.13
Polar Surface Area:
49.99
HBA:
5
HBD:
1
#RO5 Violations:
0
#Rotatable Bonds:
1
Passes Ro3:
N
QED Weighted:
0.88
Name:
2'-(5-fluoro-1-methyl-1H-indol-3-yl)-4'H-spiro[4-azabicyclo[2.2.2]octane-2,5'-[1,3]oxazole]
Mol. Formula:
C18H20FN3O
M.W.:
313.38
Type:
Small molecule
AlogP:
2.56
Polar Surface Area:
29.76
HBA:
4
HBD:
0
#RO5 Violations:
0
#Rotatable Bonds:
1
Passes Ro3:
N
QED Weighted:
0.81
Name:
2'-(3-methoxyphenyl)-4'H-spiro[4-azabicyclo[2.2.2]octane-2,5'-[1,3]oxazole]
Mol. Formula:
C16H20N2O2
M.W.:
272.35
Type:
Small molecule
AlogP:
1.94
Polar Surface Area:
34.06
HBA:
4
HBD:
0
#RO5 Violations:
0
#Rotatable Bonds:
2
Passes Ro3:
N
QED Weighted:
0.82
Name:
2'-(1-benzothien-3-yl)-4'H-spiro[4-azabicyclo[2.2.2]octane-2,5'-[1,3]oxazole]
Mol. Formula:
C17H18N2OS
M.W.:
298.41
Type:
Small molecule
AlogP:
3.14
Polar Surface Area:
24.83
HBA:
4
HBD:
0
#RO5 Violations:
0
#Rotatable Bonds:
1
Passes Ro3:
N
QED Weighted:
0.81