Dopamine D2 receptor
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ID: ALA217
Type: SINGLE PROTEIN
Synonyms: D(2) dopamine receptor | Dopamine D2 receptor | DRD2
Organism: Homo sapiens
Species Group: Homo sapiens
Protein Target Classification: Membrane receptor / Family A G protein-coupled receptor / Small molecule receptor (family A GPCR) / Monoamine receptor / Dopamine receptor
ALA ID | Relationship | Pref Name | Target Type |
---|---|---|---|
ALA3038478 | SUBSET OF | Dopamine receptor D2L/neurotensin receptor NTS1 | PROTEIN COMPLEX |
ALA2111341 | SUBSET OF | Dopamine D1 and D2 receptor | SELECTIVITY GROUP |
ALA2095169 | SUBSET OF | Dopamine receptors; D2 & D3 | SELECTIVITY GROUP |
ALA2111468 | SUBSET OF | Dopamine D2 receptor and serotonin 2a receptor | SELECTIVITY GROUP |
ALA2331075 | SUBSET OF | D2-like dopamine receptor | PROTEIN FAMILY |
ALA4296096 | SUBSET OF | D(2) dopamine receptor/Metabotropic glutamate receptor 5 | PROTEIN COMPLEX |
ALA2095396 | SUBSET OF | Dopamine receptors; D2 & D4 | SELECTIVITY GROUP |
ALA2111460 | SUBSET OF | Dopamine D2 receptor and serotonin 1a receptor | SELECTIVITY GROUP |
ALA2096905 | SUBSET OF | Dopamine receptor | PROTEIN FAMILY |
Description | Relationship | Accession |
---|---|---|
D(2) dopamine receptor | PROTEIN | P14416 |
Name | Specifications | Species reactivity | species | Application | View Details |
---|---|---|---|---|---|
ASG-5ME (anti-SLC44A4) | Human,Mouse | Human | Expand⌵ |
Name:
3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-pyrrolo[2,3-b]pyridine
Mol. Formula:
C18H19ClN4
M.W.:
326.83
Type:
Small molecule
AlogP:
3.54
Polar Surface Area:
35.16
HBA:
3
HBD:
1
#RO5 Violations:
0
#Rotatable Bonds:
3
Passes Ro3:
N
QED Weighted:
0.80
Name:
5-Bromo-7-methyl-4,6,6a,7,8,9-hexahydro-indolo[4,3-fg]quinoline-9-carboxylic acid (10b-hydroxy-5-isobutyl-2-isopropyl-3,6-dioxo-octahydro-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl)-amide
Mol. Formula:
C32H40BrN5O5
M.W.:
654.61
Type:
Small molecule
AlogP:
3.19
Polar Surface Area:
118.21
HBA:
6
HBD:
3
#RO5 Violations:
1
#Rotatable Bonds:
5
Passes Ro3:
N
QED Weighted:
0.46
Name:
6-Dipropylamino-5,6,7,8-tetrahydro-naphthalene-1,2-diol
Mol. Formula:
C16H25NO2
M.W.:
263.38
Type:
Small molecule
AlogP:
3.08
Polar Surface Area:
43.70
HBA:
3
HBD:
2
#RO5 Violations:
0
#Rotatable Bonds:
5
Passes Ro3:
N
QED Weighted:
0.80
Name:
9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline
Mol. Formula:
C19H26N2S
M.W.:
314.50
Type:
Small molecule
AlogP:
4.27
Polar Surface Area:
19.03
HBA:
2
HBD:
1
#RO5 Violations:
0
#Rotatable Bonds:
4
Passes Ro3:
N
QED Weighted:
0.91
Name:
(1-Benzyl-piperidin-4-yl)-[6-chloro-5-(4-chloro-phenylsulfanyl)-2-methyl-pyrimidin-4-yl]-amine
Mol. Formula:
C23H24Cl2N4S
M.W.:
459.45
Type:
Small molecule
AlogP:
6.32
Polar Surface Area:
41.05
HBA:
5
HBD:
1
#RO5 Violations:
1
#Rotatable Bonds:
6
Passes Ro3:
N
QED Weighted:
0.44
Name:
(1S,2R,6S,7R)-4-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-4-aza-tricyclo[5.2.1.0*2,6*]decane-3,5-dione
Mol. Formula:
C21H29N5O2
M.W.:
383.50
Type:
Small molecule
AlogP:
1.41
Polar Surface Area:
69.64
HBA:
6
HBD:
0
#RO5 Violations:
0
#Rotatable Bonds:
6
Passes Ro3:
N
QED Weighted:
0.55
Name:
[4-Chloro-6-(4-methyl-piperazin-1-yl)-5-methylsulfanyl-pyrimidin-2-yl]-methyl-amine
Mol. Formula:
C11H18ClN5S
M.W.:
287.82
Type:
Small molecule
AlogP:
1.65
Polar Surface Area:
44.29
HBA:
6
HBD:
1
#RO5 Violations:
0
#Rotatable Bonds:
3
Passes Ro3:
N
QED Weighted:
0.67
Name:
4-Chloro-2-(4-methyl-piperazin-1-yl)-3-phenylsulfanyl-quinoline
Mol. Formula:
C20H20ClN3S
M.W.:
369.92
Type:
Small molecule
AlogP:
4.79
Polar Surface Area:
19.37
HBA:
4
HBD:
0
#RO5 Violations:
0
#Rotatable Bonds:
3
Passes Ro3:
N
QED Weighted:
0.66
Name:
[4-Chloro-6-(4-methyl-piperazin-1-yl)-5-phenylsulfanyl-pyrimidin-2-yl]-methyl-amine
Mol. Formula:
C16H20ClN5S
M.W.:
349.89
Type:
Small molecule
AlogP:
3.07
Polar Surface Area:
44.29
HBA:
6
HBD:
1
#RO5 Violations:
0
#Rotatable Bonds:
4
Passes Ro3:
N
QED Weighted:
0.86
Name:
4-Chloro-5-(4-chloro-phenylsulfanyl)-2-methyl-6-(4-methyl-piperazin-1-yl)-pyrimidine
Mol. Formula:
C16H18Cl2N4S
M.W.:
369.32
Type:
Small molecule
AlogP:
3.99
Polar Surface Area:
32.26
HBA:
5
HBD:
0
#RO5 Violations:
0
#Rotatable Bonds:
3
Passes Ro3:
N
QED Weighted:
0.76