ID: ALA218
Type: SINGLE PROTEIN
Synonyms: CANN6 | Cannabinoid receptor 1 | CB-R | CB1 | CNR | CNR1
Organism: Homo sapiens
Species Group: Homo sapiens
Protein Target Classification: Membrane receptor / Family A G protein-coupled receptor / Small molecule receptor (family A GPCR) / Lipid-like ligand receptor (family A GPCR) / Cannabinoid receptor
Description | Relationship | Accession |
---|---|---|
Cannabinoid receptor 1 | PROTEIN | P21554 |
Name:
5-(4-Chloro-phenyl)-1-(2,4-dichloro-phenyl)-4-methyl-1H-pyrazole-3-carboxylic acid piperidin-1-ylamide
Mol. Formula:
C22H21Cl3N4O
M.W.:
463.80
Type:
Small molecule
AlogP:
5.94
Polar Surface Area:
50.16
HBA:
4
HBD:
1
#RO5 Violations:
1
#Rotatable Bonds:
4
Passes Ro3:
N
QED Weighted:
0.52
Name:
1-(4-Chloro-phenyl)-5-cyano-2-(2,4-dichloro-phenyl)-1H-imidazole-4-carboxylic acid (hexahydro-cyclopenta[c]pyrrol-2-yl)-amide
Mol. Formula:
C24H20Cl3N5O
M.W.:
500.82
Type:
Small molecule
AlogP:
5.75
Polar Surface Area:
73.95
HBA:
5
HBD:
1
#RO5 Violations:
2
#Rotatable Bonds:
4
Passes Ro3:
N
QED Weighted:
0.50
Name:
5-Bromo-1-(4-chloro-phenyl)-2-(2,4-dichloro-phenyl)-1H-imidazole-4-carboxylic acid (hexahydro-cyclopenta[c]pyrrol-2-yl)-amide
Mol. Formula:
C23H20BrCl3N4O
M.W.:
554.70
Type:
Small molecule
AlogP:
6.64
Polar Surface Area:
50.16
HBA:
4
HBD:
1
#RO5 Violations:
2
#Rotatable Bonds:
4
Passes Ro3:
N
QED Weighted:
0.39
Name:
5-(4-Chloro-phenyl)-1-(2,4-dichloro-phenyl)-4-methyl-1H-pyrazole-3-carboxylic acid (1,2-dimethyl-propyl)-amide
Mol. Formula:
C22H22Cl3N3O
M.W.:
450.80
Type:
Small molecule
AlogP:
6.58
Polar Surface Area:
46.92
HBA:
3
HBD:
1
#RO5 Violations:
1
#Rotatable Bonds:
5
Passes Ro3:
N
QED Weighted:
0.48
Name:
1-(4-Chloro-phenyl)-2-(2,4-dichloro-phenyl)-1H-imidazole-4-carboxylic acid azepan-1-ylamide
Mol. Formula:
C22H21Cl3N4O
M.W.:
463.80
Type:
Small molecule
AlogP:
6.02
Polar Surface Area:
50.16
HBA:
4
HBD:
1
#RO5 Violations:
1
#Rotatable Bonds:
4
Passes Ro3:
N
QED Weighted:
0.51
Name:
1-(4-Chloro-phenyl)-2-(2,4-dichloro-phenyl)-5-methyl-1H-imidazole-4-carboxylic acid [2-(4-chloro-phenyl)-ethyl]-amide
Mol. Formula:
C25H19Cl4N3O
M.W.:
519.26
Type:
Small molecule
AlogP:
7.43
Polar Surface Area:
46.92
HBA:
3
HBD:
1
#RO5 Violations:
2
#Rotatable Bonds:
6
Passes Ro3:
N
QED Weighted:
0.29
Name:
1-(4-Chloro-phenyl)-5-(2,4-dichloro-phenyl)-1H-[1,2,4]triazole-3-carboxylic acid (2-dimethylamino-ethyl)-amide
Mol. Formula:
C19H18Cl3N5O
M.W.:
438.75
Type:
Small molecule
AlogP:
4.19
Polar Surface Area:
63.05
HBA:
5
HBD:
1
#RO5 Violations:
0
#Rotatable Bonds:
6
Passes Ro3:
N
QED Weighted:
0.63
Name:
1-(4-Chloro-phenyl)-5-(2,4-dichloro-phenyl)-1H-[1,2,4]triazole-3-carboxylic acid indan-1-ylamide
Mol. Formula:
C24H17Cl3N4O
M.W.:
483.79
Type:
Small molecule
AlogP:
6.31
Polar Surface Area:
59.81
HBA:
4
HBD:
1
#RO5 Violations:
1
#Rotatable Bonds:
4
Passes Ro3:
N
QED Weighted:
0.37
Name:
1-(4-Chloro-phenyl)-5-(2,4-dichloro-phenyl)-1H-[1,2,4]triazole-3-carboxylic acid (4-methyl-cyclohexyl)-amide
Mol. Formula:
C22H21Cl3N4O
M.W.:
463.80
Type:
Small molecule
AlogP:
6.20
Polar Surface Area:
59.81
HBA:
4
HBD:
1
#RO5 Violations:
1
#Rotatable Bonds:
4
Passes Ro3:
N
QED Weighted:
0.50
Name:
1-(4-Chloro-phenyl)-2-(2,4-dichloro-phenyl)-5-ethynyl-1H-imidazole-4-carboxylic acid (hexahydro-cyclopenta[c]pyrrol-2-yl)-amide
Mol. Formula:
C25H21Cl3N4O
M.W.:
499.83
Type:
Small molecule
AlogP:
5.86
Polar Surface Area:
50.16
HBA:
4
HBD:
1
#RO5 Violations:
1
#Rotatable Bonds:
4
Passes Ro3:
N
QED Weighted:
0.46