Your company account is blocked and you cannot place orders. If you have questions, please contact your company administrator.

Dopamine D4 receptor

Name And Classification

ID:  ALA219

Type:  SINGLE PROTEIN

Synonyms:   D(2C) dopamine receptor | D(4) dopamine receptor | Dopamine D4 receptor | DRD4

Organism:  Homo sapiens

Species Group:  Homo sapiens

Protein Target Classification:   Membrane receptor / Family A G protein-coupled receptor / Small molecule receptor (family A GPCR) / Monoamine receptor / Dopamine receptor

Target Relations

ALA IDRelationshipPref NameTarget Type

Target Components

DescriptionRelationshipAccession
D(4) dopamine receptorPROTEINP21917

Associated Recombinant Proteins

The page will load shortly, Thanks for your patience!
NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Active Ligands

  1. Tetrahydrouridine
    ALA268558

    Name:
    1-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-pyrazolo[5,1-a]isoquinoline

    Mol. Formula:
    C22H21ClN4

    M.W.:
    376.89

    Type:
    Small molecule

    AlogP:
    4.46

    Polar Surface Area:
    23.78

    HBA:
    4

    HBD:
    0

    #RO5 Violations:
    0

    #Rotatable Bonds:
    3

    Passes Ro3:
    N

    QED Weighted:
    0.53

    DETAILS
  2. Tetrahydrouridine
    ALA269576

    Name:
    3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-pyrazolo[1,5-a]quinoline

    Mol. Formula:
    C22H21ClN4

    M.W.:
    376.89

    Type:
    Small molecule

    AlogP:
    4.46

    Polar Surface Area:
    23.78

    HBA:
    4

    HBD:
    0

    #RO5 Violations:
    0

    #Rotatable Bonds:
    3

    Passes Ro3:
    N

    QED Weighted:
    0.53

    DETAILS
  3. Tetrahydrouridine
    ALA7505

    Name:
    3-(4-Methyl-piperazin-1-ylmethyl)-pyrazolo[1,5-a]pyridine

    Mol. Formula:
    C13H18N4

    M.W.:
    230.31

    Type:
    Small molecule

    AlogP:
    1.08

    Polar Surface Area:
    23.78

    HBA:
    4

    HBD:
    0

    #RO5 Violations:
    0

    #Rotatable Bonds:
    2

    Passes Ro3:
    N

    QED Weighted:
    0.77

    DETAILS
  4. Tetrahydrouridine
    ALA269202

    Name:
    3-[4-(3-Chloro-phenyl)-piperazin-1-ylmethyl]-pyrazolo[1,5-a]pyridine

    Mol. Formula:
    C18H19ClN4

    M.W.:
    326.83

    Type:
    Small molecule

    AlogP:
    3.31

    Polar Surface Area:
    23.78

    HBA:
    4

    HBD:
    0

    #RO5 Violations:
    0

    #Rotatable Bonds:
    3

    Passes Ro3:
    N

    QED Weighted:
    0.74

    DETAILS
  5. Tetrahydrouridine
    ALA273860

    Name:
    3-(4-Phenyl-piperazin-1-ylmethyl)-pyrazolo[1,5-a]pyridine

    Mol. Formula:
    C18H20N4

    M.W.:
    292.39

    Type:
    Small molecule

    AlogP:
    2.66

    Polar Surface Area:
    23.78

    HBA:
    4

    HBD:
    0

    #RO5 Violations:
    0

    #Rotatable Bonds:
    3

    Passes Ro3:
    N

    QED Weighted:
    0.74

    DETAILS
  6. Tetrahydrouridine
    ALA7508

    Name:
    3-[4-(4-Iodo-phenyl)-piperazin-1-ylmethyl]-pyrazolo[1,5-a]pyridine

    Mol. Formula:
    C18H19IN4

    M.W.:
    418.28

    Type:
    Small molecule

    AlogP:
    3.26

    Polar Surface Area:
    23.78

    HBA:
    4

    HBD:
    0

    #RO5 Violations:
    0

    #Rotatable Bonds:
    3

    Passes Ro3:
    N

    QED Weighted:
    0.61

    DETAILS
  7. Tetrahydrouridine
    ALA268190

    Name:
    3-(4-Cyclohexyl-piperazin-1-ylmethyl)-pyrazolo[1,5-a]pyridine

    Mol. Formula:
    C18H26N4

    M.W.:
    298.43

    Type:
    Small molecule

    AlogP:
    2.78

    Polar Surface Area:
    23.78

    HBA:
    4

    HBD:
    0

    #RO5 Violations:
    0

    #Rotatable Bonds:
    3

    Passes Ro3:
    N

    QED Weighted:
    0.87

    DETAILS
  8. Tetrahydrouridine
    ALA21252

    Name:
    N-{4-[4-(4-Chloro-phenyl)-piperazin-1-yl]-butyl}-acetamide

    Mol. Formula:
    C16H24ClN3O

    M.W.:
    309.84

    Type:
    Small molecule

    AlogP:
    2.38

    Polar Surface Area:
    35.58

    HBA:
    3

    HBD:
    1

    #RO5 Violations:
    0

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.82

    DETAILS
  9. Tetrahydrouridine
    ALA278288

    Name:
    N-{5-[4-(4-Chloro-phenyl)-piperazin-1-yl]-pentyl}-2,2-dimethyl-propionamide

    Mol. Formula:
    C20H32ClN3O

    M.W.:
    365.95

    Type:
    Small molecule

    AlogP:
    3.79

    Polar Surface Area:
    35.58

    HBA:
    3

    HBD:
    1

    #RO5 Violations:
    0

    #Rotatable Bonds:
    7

    Passes Ro3:
    N

    QED Weighted:
    0.75

    DETAILS
  10. Tetrahydrouridine
    ALA423287

    Name:
    N-{3-[4-(4-Chloro-phenyl)-piperazin-1-yl]-propyl}-2,2-dimethyl-propionamide

    Mol. Formula:
    C18H28ClN3O

    M.W.:
    337.90

    Type:
    Small molecule

    AlogP:
    3.01

    Polar Surface Area:
    35.58

    HBA:
    3

    HBD:
    1

    #RO5 Violations:
    0

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.84

    DETAILS