ID: ALA219
Type: SINGLE PROTEIN
Synonyms: D(2C) dopamine receptor | D(4) dopamine receptor | Dopamine D4 receptor | DRD4
Organism: Homo sapiens
Species Group: Homo sapiens
Protein Target Classification: Membrane receptor / Family A G protein-coupled receptor / Small molecule receptor (family A GPCR) / Monoamine receptor / Dopamine receptor
ALA ID | Relationship | Pref Name | Target Type |
---|
Description | Relationship | Accession |
---|---|---|
D(4) dopamine receptor | PROTEIN | P21917 |
Name | Specification and purity | Expression system | Protein label | Activity | View Details |
---|
Name:
1-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-pyrazolo[5,1-a]isoquinoline
Mol. Formula:
C22H21ClN4
M.W.:
376.89
Type:
Small molecule
AlogP:
4.46
Polar Surface Area:
23.78
HBA:
4
HBD:
0
#RO5 Violations:
0
#Rotatable Bonds:
3
Passes Ro3:
N
QED Weighted:
0.53
Name:
3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-pyrazolo[1,5-a]quinoline
Mol. Formula:
C22H21ClN4
M.W.:
376.89
Type:
Small molecule
AlogP:
4.46
Polar Surface Area:
23.78
HBA:
4
HBD:
0
#RO5 Violations:
0
#Rotatable Bonds:
3
Passes Ro3:
N
QED Weighted:
0.53
Name:
3-(4-Methyl-piperazin-1-ylmethyl)-pyrazolo[1,5-a]pyridine
Mol. Formula:
C13H18N4
M.W.:
230.31
Type:
Small molecule
AlogP:
1.08
Polar Surface Area:
23.78
HBA:
4
HBD:
0
#RO5 Violations:
0
#Rotatable Bonds:
2
Passes Ro3:
N
QED Weighted:
0.77
Name:
3-[4-(3-Chloro-phenyl)-piperazin-1-ylmethyl]-pyrazolo[1,5-a]pyridine
Mol. Formula:
C18H19ClN4
M.W.:
326.83
Type:
Small molecule
AlogP:
3.31
Polar Surface Area:
23.78
HBA:
4
HBD:
0
#RO5 Violations:
0
#Rotatable Bonds:
3
Passes Ro3:
N
QED Weighted:
0.74
Name:
3-(4-Phenyl-piperazin-1-ylmethyl)-pyrazolo[1,5-a]pyridine
Mol. Formula:
C18H20N4
M.W.:
292.39
Type:
Small molecule
AlogP:
2.66
Polar Surface Area:
23.78
HBA:
4
HBD:
0
#RO5 Violations:
0
#Rotatable Bonds:
3
Passes Ro3:
N
QED Weighted:
0.74
Name:
3-[4-(4-Iodo-phenyl)-piperazin-1-ylmethyl]-pyrazolo[1,5-a]pyridine
Mol. Formula:
C18H19IN4
M.W.:
418.28
Type:
Small molecule
AlogP:
3.26
Polar Surface Area:
23.78
HBA:
4
HBD:
0
#RO5 Violations:
0
#Rotatable Bonds:
3
Passes Ro3:
N
QED Weighted:
0.61
Name:
3-(4-Cyclohexyl-piperazin-1-ylmethyl)-pyrazolo[1,5-a]pyridine
Mol. Formula:
C18H26N4
M.W.:
298.43
Type:
Small molecule
AlogP:
2.78
Polar Surface Area:
23.78
HBA:
4
HBD:
0
#RO5 Violations:
0
#Rotatable Bonds:
3
Passes Ro3:
N
QED Weighted:
0.87
Name:
N-{4-[4-(4-Chloro-phenyl)-piperazin-1-yl]-butyl}-acetamide
Mol. Formula:
C16H24ClN3O
M.W.:
309.84
Type:
Small molecule
AlogP:
2.38
Polar Surface Area:
35.58
HBA:
3
HBD:
1
#RO5 Violations:
0
#Rotatable Bonds:
6
Passes Ro3:
N
QED Weighted:
0.82
Name:
N-{5-[4-(4-Chloro-phenyl)-piperazin-1-yl]-pentyl}-2,2-dimethyl-propionamide
Mol. Formula:
C20H32ClN3O
M.W.:
365.95
Type:
Small molecule
AlogP:
3.79
Polar Surface Area:
35.58
HBA:
3
HBD:
1
#RO5 Violations:
0
#Rotatable Bonds:
7
Passes Ro3:
N
QED Weighted:
0.75
Name:
N-{3-[4-(4-Chloro-phenyl)-piperazin-1-yl]-propyl}-2,2-dimethyl-propionamide
Mol. Formula:
C18H28ClN3O
M.W.:
337.90
Type:
Small molecule
AlogP:
3.01
Polar Surface Area:
35.58
HBA:
3
HBD:
1
#RO5 Violations:
0
#Rotatable Bonds:
5
Passes Ro3:
N
QED Weighted:
0.84